Luckily, the Native Americans told them about a tea prepared from the bark of a certain tree, which miraculously led to complete recovery. For most people, pine bark extract doesn't cause any side effects. Headaches. whole-body health. Researchers suggest that it may have stronger benefits than elastic compression stockings. Pycnogenol can help control blood pressure, which helps improve overall heart health. It may cause side effects such as: Dizziness. $109.99. During the first month on L-arginine, only five percent of patients experienced normal erection. In the following sections, well discuss the common forms and dosages of Pycnogenol that are commercially available. In one human study, some of the reported side effects of chanca piedra supplementation included: abdominal pain. Studies have found that supplementing with pycnogenol effectively strengthens the blood vessels, stabilizing blood pressure. There were 88 in the control group and 81 in the Pycnogenol group. Symptoms of menopausal syndrome, also known as climacteric syndrome, include: hot flashes; chills; headache; and depression. All of our content is written by scientists and people with a strong science background. In one study, 10 patients were treated with placebo and 30 patients were treated with Pycnogenol (100 mg twice or three times daily for two months). Moreover, Pycnogenol treatment reduced the use of painkillers. The goal of one study was to evaluate whether or not Pycnogenol could prevent edema (fluid build-up) during long-haul flights in healthy people. Note that the numbers in parentheses (1, 2, etc.) The positive improvements in symptoms were greater among those taking Pycnogenol. According to a study in 59 cancer patients, Pycnogenol (150 mg/day) may reduce side effects associated with radiation or chemotherapy, including mouth soreness and ulcers, mouth and eye dryness, nausea, vomiting, diarrhea and weight loss [78]. Boost gastrointestinal health. These antioxidants scavenge those damaging free radicals in an effort to eliminate them, ultimately preventing disease. Also, be sure to talk with your doctor first if you have an underlying medical condition or take other medications. We believe that the most accurate information is found directly in the scientific source. Blazs G, et al. The dosage in most clinical studies varied between 50-360 mg/day. painful urination. (3), Ototoxicity is ear poisoning and can occur when exposed to certain drugs or chemicals, such as cisplatin, that damage the inner ear or the vestibulocochlear nerve. Healthline Media does not provide medical advice, diagnosis, or treatment. Pycnogenol: A miracle component in reducing ageing and skin disorders. A high number signals high blood pressure. Along with the rest of the crew, he developed symptoms of vitamin-C deficiency. But what makes this miracle ingredient so amazing? Eye health. You can gradually increase how much you take once you get a better idea of how your body reacts to it. They could interact with medicines to suppress the immune system, chemotherapy drugs, and blood thinners. Learn about this tree-based pill and how it might be able to help you. In another study, Pycnogenol increased glutathione levels and total antioxidants after a month in children with ADHD [42, 43]. As I mentioned, pine bark extract is superior when it comes to antioxidants. Joe Cohen flipped the script on conventional and alternative medicine and it worked. In patients with chronic venous insufficiency, the number of muscle cramps decreased from 6.3 to 2.6; in athletes from 8.6 to 2.4. Pycnogenol (100 mg/day) improved menopausal symptoms and quality of life in a clinical trial of 35 women after 8 weeks [68]. However, it can also be used topically. Taking pine bark extract supports healthy blood pressure. If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please leave a comment or contact us at [emailprotected]. Pycnogenol suppresses inflammation and regulates the production of nitric oxide - a . Pine bark extract provides many benefits to the skin, including reducing the signs of aging. SelfDecode does not treat, diagnose or cure any conditions, Blood clots form as a result of platelet aggregation, which is the platelets in the blood clumping together. Patients were given 100 milligrams of Pycnogenol, a branded version of pine bark extract, for 12 weeks, with continued anti-diabetic treatment. If you are taking blood thinners, do not take pine bark extract or Pycnogenol unless approved by your doctor. So begins my look at the natural supplement, pycnogenol (French Maritime Pine Bark Extract)benefits. All rights reserved. Some studies have suggested it may modestly improve blood pressure, cholesterol, and C-reactive protein. The effects of the pine bark extract showed significant lower levels of blood glucose and improved endothelial function when compared to placebo, concluding that supplementation of Pycnogenol for treating conventional diabetes may be beneficial. Trees of this pine have been naturalized in Australia and New Zealand, where most Enzogenol is now made [7]. In a smaller study of 58 people, pycnogenol reduced the inflammatory marker CRP [49, 50]. In the Pycnogenol-treated group, blood sugar levels were significantly lowered as compared to those not on Pycnogenol. Some pycnogenol supplements are mixed with other antioxidants, such as vitamin C. Pine bark extracts other than pycnogenol are also sold. (14, 15). Pine bark extract is usually taken by mouth in capsule form. Learn more. Pycnogenol lotions applied postirradiation reduced this immunosuppression to 22% (0.05% Pycnogenol) and 13% (0.1% Pycnogenol). The study participants symptoms started to return a month after they stopped taking pine bark extract. A new peer-reviewed study, published in the Bratislava Medical Journal, shows that daily supplementation with the natural antioxidant, Pycnogenol, a French maritime pine bark extract, can improve the symptoms of ED.. She is a strong advocate of integrating scientific knowledge and holistic medicine. Symptoms include swelling in ankles and legs, discolored skin and, if the skin is broken, the development of leg ulcers. In 1534, a French ship led by the famous explorer Jacques Cartier became stranded in ice near Quebec, Canada. Pycnogenol French maritime pine bark extract's 4 basic properties. This makes it very hard to set a standard dose. DIM and other plant indoles are found in . A study with four groups of 30 patients each were studied: (1) systemic Pycnogenol and local application; (2) local Pycnogenol only; (3) oral Pycnogenol and (4) medications only (control). This is thought to be due to pine bark extracts ability to reduce oxidative stress and inflammation. Sort By. Pycnogenol alleviated adverse effects in cancer patients, Pycnogenol improved working memory in older adults, Pycnogenol lowered the use of analgesic drugs in dysmenorrhea (severe menstrual pain), Pycnogenol reduced symptoms in endometriosis comparable to leuprorelin, the standard drug for this condition, Pycnogenol was found to be effective for sun-caused hyperpigmented skin, Pycnogenol reduced the inflammation in lupus patients, Pycnogenol reduced gingival bleeding and plaque formation. He learned about the seemingly omnipotent antioxidant within it and how those antioxidants increase the absorption of vitamin C. Continued research showed that the pine bark contained flavonols and bioflavonoids, which hold tissue-repairing properties. Although the preliminary studies show many health benefits with the use of Pycnogenol, future larger and better studies are needed. Since components of Pycnogenol can be modified during digestion and absorption as well as by the liver, diseases that affect the gut or liver may increase or decrease its effects [84]. Pycnogenol is the registered trademark brand name of French maritime pine bark extract. (13). Once youre sure that you dont have any negative reactions, you may be able to increase your dosage according to the label. Pycnogenol is considered safe when taken orally in a dose of 50 to 450 mg per day for one year. Blood pressure is an important measure of how much blood is pumping from your heart to the rest of your body . - Apply a hot compress to the anus or soaking it in a shallow tub of hot water several times a day. Ac., CYT, 12 Benefits of Ginkgo Biloba (Plus Side Effects & Dosage), Tongkat Ali (Eurycoma longifolia): Everything You Need to Know, reduce blood sugar levels in people with diabetes, are within two weeks of a scheduled surgery, medications, herbs, and supplements that affect the blood or clotting. 1 Anti-Aging Beverage, Daniel Fast: Benefits for Your Spiritual, Emotional and Physical Health, 15 Fermented Foods for a Healthy Gut and Overall Health, 9 Proven Black Seed Oil Benefits that Boost Your Health, L-Glutamine Benefits Leaky Gut & Metabolism, Chia Seeds Benefits: The Omega-3, Protein-Packed Superfood, Apple Cider Vinegar Benefits for Weight Loss, Skin Health, Cholesterol & More, What Is a Marionberry? Another study found this supplement can even halt progression of vision . Pycnogenol is considered possibly safe when taken orally or when applied topically as a cream or ointment. (9), Related:Top 7 Benefits of Green Tea: The No. 1) Encourages Healthy Blood Pressure. Two studies illustrate the possibilities: One was a randomized, double-blind, placebo-controlled, crossover study in which 26 asthmatic patients were given either a maximum of 200 mg a day of Pycnogenol or placebo for the first period of four weeks and then crossed over to the alternate treatment for the next four weeks. Lowers Blood Pressure. While these results are promising, there isnt enough research to fully understand the effect of antioxidant levels on ADHD symptoms. Top 9 Natural Allergy Relief Home Remedies - Dr. Axe 1 week ago from draxe.com Eat an Anti-Inflammatory, Alkaline Diet. All Pycnogenol-treated patients responded favorably in contrast to placebo treatment. ", Mayo Clinic: High blood pressure (hypertension)., Panminerva Medica: "Pycnogenol improvements in asthma management. which enables users to obtain detailed information and reports based on their genome. In a study of 50 overweight people, a combination product (Pycnogenol, Madeglucyl, and starches called Glucaffect) reduced weight, BMI, blood glucose, and HbA1C after 8 weeks [30]. In a double-blind, placebo-controlled, randomized, crossover study, 50 patients with erectile dysfunction (ED) were treated with either L-arginine plus Pycnogenol or placebo for a month. A 2017 review reported on the many benefits of using pine bark extract to reduce the effects of aging on skin. 3. Natural Factors Pycnogenol 25mg 60 Veggie Caps. 7. DOI: Marini A, et al. SelfDecode is a personalized health report service, In clinical research, doses up to about 300 mg/day have been used for up to one year without major safety concerns [33, 37]. In another study, 45 men with ED were given 1.7 grams of L-arginine a day during the first month, 40 mg Pycnogenol twice daily during the second month, and the dose increased to three 40-mg Pycnogenol doses daily during the third month. Research suggests that taking pycnogenol improves mental function and memory in both young adults and the elderly. editor, The Gale Encyclopedia of Alternative Medicine, third edition, 2009. Pycnogenol is a compound of natural chemicals. Pycnogenol was gradually increased to 120 mg/day over this time period, while the l-arginine was maintained at 1.7 g/day throughout. It can also stabilize mast cells, which release histamine and trigger allergic reactions. The extract has been widely studied for the past 40 . Pycnogenol lowered leukotrienes as well. Another study in 2012 showed that Pycnogenol alone, at a dose of 75 mg/day, increased skin hydration by 8% after just 6 weeks; in women with dry skin at baseline the increase was 21%. This article is based on scientific evidence, written by experts and fact checked by our trained editorial staff. Berberine is a compound extracted from several plants. ", Journal of Medicinal Food: "Review on Sustained Relief of Osteoarthritis Symptoms with a Proprietary Extract from Pine Bark, Pycnogenol. According to a large analysis, Pycnogenol may reduce osteoarthritis symptoms and pain short-term [45, 46]. Side effects. For most people, pine bark extract doesnt cause any side effects. Risks. This bark extract has been around for about 450 years. $47.99. The same ingredient can be found in grapeseed oil, the skin of peanuts and witch hazel bark. 10 Ways to Control Blood Sugar without Medication, Pycnogenol (French Maritime Pine Bark Extract): 12 Benefits According to Studies, Reduces leaky blood vessels by making the wall proteins (collagen, elastin) more resistant to damage, Helps maintain high vitamin C and E blood levels for their antioxidant effects, Inhibits platelet aggregation like low-dose aspirin, Reduces hardening in the arteries by increasing nitric oxide production in blood vessels, leading to greater dilatation, Counteracts the damaging effects of ultraviolet radiation, Stimulates the immune system by boosting T and B cell functions, Protects brain cells from toxic chemicals. Here are some basic guidelines as reported by WebMD: While most studies do not indicate major side effects, pine bark extract may cause irritability and fatigue, and could interact with other drugs. However, research on these two groups is limited [71, 15]. SelfHacked has the strictest sourcing guidelines in the health industry and we almost exclusively link to medically peer-reviewed studies, usually on PubMed. Pycnogenol pine bark extracts contain a unique blend of flavonoids whose antioxidant action is over is 50 times more powerful than vitamin E, 20 times more powerful than vitamin C and 16 times more active than grapeseed extracts. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. 2. (8). Its been noted that taking OPCs and vitamin C supplements at the same time could increase blood pressure if you have hypertension. Help your body fight the effects of normal aging. It also may help those on blood pressure medications to reduce their dose [32]. However, a study of 24 adults with ADHD found that pycnogenol did not improve ADHD symptoms better than placebo. They were treated with 200 mg of Pycnogenol daily or with placebo. Optimal doses of pycnogenol have not been set for any condition. Erythritol: Is This Healthy Sweetener the Real Deal? Pycnogenol-treated patients reported significant improvement with knee pain, as compared to the placebo group. In a study of 100 healthy women mostly in their early 40s with mild sexual dysfunction, a combination product with Pycnogenol (Lady Prelox) improved sexual function over 8 weeks [74]. While pine bark extract is thought to be safe for children, they should only take it for a few weeks at a time. It is found primarily in southwestern France and is used to help people with asthma, allergies, hay fever, and other health conditions.. Pycnogenol accelerates wound healing and reduces scar formation [Abstract]. 3. If a blood clot blocks the normal blood flow, it is known as thrombosis. Several studies show how Pycnogenol helps block platelet formation and thus helps prevent thrombosis. Pine bark extract can help reduce muscle soreness and may help improve conditions relating to poor circulation, high blood pressure, osteoarthritis, diabetes, ADHD, female reproductive issues, skin, erectile dysfunction, eye disease and sports stamina. A study of 30 women found that Pycnogenol (75 mg/day) may reduce the skin area affected by melasma as well as lower symptoms of fatigue, constipation, body pain, and anxiety [62]. - Please read carefully and implement principles included in the Health Recovery Plan. Organika Pycnogenol 50mg 50 Tablets . Pine bark extract can be found in liquid, tablet or capsule form containing 85 percent to 90 percent OPCs. While it may seem intimidating at first, counting macros is a common Erythritol is now one of the most popular natural zero-calorie sweeteners available. Comment * document.getElementById("comment").setAttribute( "id", "a79cdfe7a30d8f84d45d97f833c00b8c" );document.getElementById("a6cbe26769").setAttribute( "id", "comment" ); Save my name, email, and website in this browser for the next time I comment. In 7 volunteers, Pycnogenol (300 mg) for 5 days may reduce the activity of a crucial inflammatory gene (NF-B) [53]. No side effects were noted, unlike its synthetic counterpart. Score one for diabetes control and fewer risk factors for the heart. (2006). Ana spent years working with patients who suffer from various mental health issues and chronic health problems. Pycnogenol seems to help with asthma and allergies. In one clinical trial of 156 osteoarthritis patients, pycnogenol reduced pain, stiffness, swelling, and improved joint function after 3 months. According to the lab results of 10 volunteers, a higher Pycnogenol dose (300 mg) may impact these enzymes after just 30 minutes [52]. The information in our articles is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. Normalization of cardiovascular risk factors in peri-menopausal women with Pycnogenol [Abstract]. There havent been enough studies yet to change practice protocols for treating children. In mice, luteolin prevented inflammation and allergic response in the lungs and nose by inhibiting inflammatory cytokines: IL-4, IL-5, and IL-1 3 []. Organika Pycnogenol 50mg 100 Tablets. (2004). This ensures that there is a healthy flow of blood to and from the heart. There is insufficient evidence to support the use of Pycnogenol for any of the uses listed below. Take Helpful Supplements. Side Effects of Pycnogenol. As noted, aspirin can cause severe gastrointestinal issues. This review noted that pine bark extract may also help with: In addition to its skin-healing properties, pine bark extract also shows promise for helping children manage ADHD symptoms. Pycnogenol improved symptoms, circulation, and reduced complications in 156 people with deep vein thrombosis (blot clots in deep leg veins) in a 12-month study. There are several causes for erectile dysfunction, such as neurological and psychological issues. Asthma is caused by inflammation in the lungs, which makes it hard to breathe. We don't yet know what the best dose to use is, but studies have used two 50 mg Pycnogenol capsules per day. But a month after pycnogenol was stopped, the symptoms came back, suggesting that it may need to be used regularly to achieve the benefits [41]. Research indicates that Pycnogenol provides an increase in endurance performance of trained athletes. Tell your doctor about any supplements you're taking, even if they're natural. The usual recommended duration of treatment for topical application is 7 days for Pycnogenol cream and 6 weeks for Pycnogenol powder. Pycnogenol treatment resulted in more normal-looking sperm. Interesting activities, new dishes in restaurants, specialty ingredients, explanations of some netizens questions, etc.Hu Xuan is even helping Fatty s company s tourism manager, managing with Vice President Du Meixin, such as arranging guests reasonably.By the way.Dad, I want to tell you something.I plan to invest in the hotels and entertainment centers in the . It also reduced LDL cholesterol at a slightly lower dose (125 mg/day) in those with type 2 diabetes in a clinical trial of 48 people after 12 weeks. Considering that about 1 of 3 adults in the U . Pycnogenol seems well-tolerated for use in adults for up to 6 months. Here are the many health benefits believed to be possible with Pycnogenol: Now lets dive into the first condition it could help treat. The women taking Pycnogenol also experienced improvement in fatigue, sleep, concentration, memory, dizziness, and mood, including less irritability. nausea. It has been studied for its effects on everything from mental function to treating high blood pressure. Certain studies used combination products, so its unknown what the contribution of Pycnogenol itself was. Diabetic retinopathy is a type of eye injury caused by complications from diabetes. According to a study of 11 patients with lupus, pycnogenol may reduce symptoms, inflammation, and oxidative stress [54]. Learn more about how to get even skin tone. A total of 40 patients with retinopathy (damage to the retina part of the eye) from diabetes and other vascular causes were enrolled in one study. It decreased concussion symptoms in 42 student-athletes with a history of sports-related concussions after 6 weeks. A trial of children with ADHD found that Pycnogenol may improve attention, possibly by increasing the total antioxidant status and reducing DNA damage. It comes from the bark of a European pine tree. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. Based on another study of 6 trained and 7 untrained people, an antioxidant combination product containing Pycnogenol (Lactaway) may increase endurance. Pycnogenol (100 mg/day) given to 44 older healthy people with high oxidative stress improved cognitive function, attention, mental performance, and reduced oxidative stress after 12 months [21]. Read More: Health Benefits of Peanut Butter. Buy Healthy Origins Pycnogenol 100 mg (Nature's Super Antioxidant, Non-GMO, Gluten Free, Cardiovascular Support), . Pycnogenol and Pine Bark Extract Supplements. One study found that Pycnogenol may reduce the activity of the inflammatory enzymes COX1 and COX2, similar to how NSAID drugs work. Herbal supplements are not regulated by the Food and Drug Administration (FDA), so they may not be up to the same safety standards as medications that have gone through clinical testing and drug trials. Commonly called arthritis, osteoarthritis is caused when the cartilage on your joints begins to wear down. The study provided clear evidence that Pycnogenol does, indeed, offer photoprotection however, it came out even better than expected, showing that it may be used to reduce hyperpigmentation of human skin while improving the skin barrier function and extracellular matrix homeostasis. (6). Pine bark extract appears to reduce the creation of free radicals, which are molecules linked to several skin conditions. While much of this is positive, it will be a while before doctors routinely recommend this dietary supplement for these conditions. It also slightly decreased blood pressure and increased testosterone [67]. , Allergy: "Leukotriene E4 plasma levels in adult asthmatic patients with variable disease severity. High-dose Pycnogenol (360 mg/day) for 4 weeks had the same LDL-lowering benefits in another study of 40 people [32, 56]. A systematic review of 14 studies found that Pycnogenol gum or mouthwashes may reduce dental plaque, but the quality of evidence is low [58, 59]. Pycnogenol is known under different names in some countries, such as Oligopin, and Flavangenol in Japan [4, 5]. 40 years of research has been dedicated to establishing the safety of Pycnogenol and its benefits for human health. Helps maintain high vitamin C and E blood levels for their antioxidant effects. It can also be found as creams, lotions or ointments, typically containing 0.5 percent to 2 percent pine bark extract. 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