J Clin Epidemiol. Uterine fibroids. Who Can Get Fibroids| Symptoms,Causes, Diagnosis of Uterine Fibroids In some cases, though, health care providers find fibroids during a routine gynecological exam. MANAIG-UTERINE-FIBROIDS.pdf - Nursing Care Plan-Uterine But fibroids can grow during pregnancy and about 20 to 30% of cases, and that causes pain. Across types of interventions, direct annual healthcare costs in the United States are projected to exceed $9.1 billion. If there's a concern for cancer, you may be referred to a specialist to discuss whether a hysterectomy is the best option rather than trying uterine sparing treatments. https://www.uptodate.com/contents/search. Nursing Care Plan 2021. In: Netter's Obstetrics and Gynecology. the unsubscribe link in the e-mail. The final report does not necessarily represent the views of individual reviewers. Am J Obstet Gynecol. When no studies are available for an outcome or comparison of interest, we will grade the evidence as insufficient. We will retrieve and review all articles that meet our predetermined inclusion criteria from abstract screening or for which we have insufficient information to make a decision about eligibility. For all procedures except hysterectomy, seedlings tiny tumors that your doctor doesn't detect during surgery could eventually grow and cause symptoms that warrant treatment. All rights reserved. Anti-progesterone effect - reduces action and number of progesterone receptors in fibroids and myometrium. . However, studies do show that fibroids can continue to keep growing after menopause because there are other tissues in our body that produce estrogen besides the ovaries. Levonorgestrel-releasing intrauterine system, Bayer Healthcare Pharmaceuticals, Inc, Whippany, NJ, USA, Merck Sharp & Dohme Limited, Hertfordshire, UK, Gynecare Morcellex Tissue Morcellator Models Mx0100 And Mx0100r, Pks Plasma Morcellator Models 962000pk 3620pk, Ksea Sawahle Electromechanical Morcellator, Ksea Rotocut G1 Electromechanical Morcellator, Coherent Tissue Morcellator Kit And Accessories, Lumenis Versacut Tissue Morcellator System, Morce Power Plus And Variocarve Morcellator, Riwo Cut-Morcellator Existing Of Knife/Cutting Sleeve/Protection Sleeve/Claw Grasping Forceps, Iur Reciprocating Morcellator Model # 7210517, Truclear Morcellation System And Truclear Morcellators, VizAblate not FDA-approved for use in the U.S.), Thermachoice Thermal Balloon Ablation system, NovaSure Impedance Controlled Endometrial Ablation System, Doppler-Guided Uterine Artery Occlusion (DUAO) Device (Gynecare Gynocclude D-UAO), MyoSure Hysteroscopic Tissue Removal System (Hysteroscopic), Notes: Drug therapy[mh] includes hormone therapy; Surgical procedures, operative[mh] includes ultrasound ablation, embolization, and hysterectomy, ((leiomyoma[mh]) OR (fibroma[mh] AND (uterine diseases[mh] OR uterus[mh]))), (Uterine[tiab] AND (fibroma*[tiab] OR fibroid*[tiab] OR leiomyoma*[tiab] OR myoma*[tiab] OR fibromyoma*[tiab])) OR (submucous fibroid*[tiab] OR submucosal fibroid*[tiab] OR Intramural fibroids [tiab]) NOT medline[sb], (((((("Mifepristone"[Mesh] OR "ulipristal"[Supplementary Concept]) OR "Anti-Inflammatory Agents, Non-Steroidal"[Mesh]) OR "Antifibrinolytic Agents"[Mesh]) OR "Goserelin"[Mesh]) OR "cetrorelix"[Supplementary Concept]) OR "Selective Estrogen Receptor Modulators"[Mesh]) OR "Levonorgestrel"[Mesh], therapy[sh:noexp] OR drug therapy[mh] OR drug therapy[sh] OR complementary therapies[mh] OR Treatment outcome[mh], (Mifepristone[tiab] OR Ulipristal acetate[tiab] OR NSAID[tiab] OR antifibrinolytic[tiab] OR Goserelin[tiab] OR cetrorelix acetate[tiab] OR Selective estrogen receptor modulators[tiab] OR SERM[tiab] OR mirena[tiab] OR lng-ius[tiab] OR levonorgestrel-releasing intrauterine system[tiab]) NOT medline[sb], surgery[sh] OR surgical procedures, operative[mh] OR embolization, therapeutic[mh], (Hysterectomy[tiab] OR myomectomy[tiab] OR emboliz*[tiab] OR ablation[tiab] OR ultrasound[tiab] OR uterine artery occlusion[tiab] OR Uterine artery embolization[tiab] OR UAE[tiab]) NOT medline[sb], ("Electrosurgery/adverse effects"[Mesh]) OR "Uterine Myomectomy/adverse effects"[MeSH] OR morcellat*, ("Electrosurgery/adverse effects"[Mesh] AND uterine) OR "Uterine Myomectomy/adverse effects"[MeSH] OR morcellat*, Hysterectomy via abdominal, vaginal, laparoscopic, or robotic approach, Myomectomy via laparotomy, laparoscopy, hysteroscopy, or robotic approach, Uterine artery embolization including ligation and occlusion, Ablative procedures (e.g., MRgFUS, cryoablation), Progestin-containing intrauterine devices, Medications to improve or resolve symptoms or reduce size of fibroids, Inactive treatment including wait list control, expectant management, or placebo, Conversion to alternate operative procedure, Misdirected embolization / non-target tissue embolization, Uterine fibroid treatment/intervention outcome (KQs 1, 2), Harm or adverse event from uterine fibroid treatment/intervention (KQs 1-4), Sufficient detail of methods and results to enable data extraction (KQs 1-4), Reports outcome data by target population or intervention (KQs 1-4), Baird DD, Dunson DB, Hill MC, et al. Nursing Diagnosis and Interventions for Uterine Fibroids 1. Depending upon the quantity and size of the sources for the data, we may attempt to establish thresholds to assess overall high, medium or low risk of bias.25. Acute Pain. Patient education: Uterine fibroids (Beyond the Basics) - UpToDate It is defined as excessive menstrual bleeding with a loss of more than 80ml of blood per month. Large fibroids may cause infertility by preventing a fertilised egg from implanting in the womb or blocking the fallopian tubes, although this is rare. We may include in the analysis high of risk of bias studies that have a large sample size or that evaluate outcomes not addressed in other studies. Differences between the reviewers will be adjudicated by a senior team member or via team discussion. Although aetiology and natural history of the conditions are markedly different, symptoms can overlap and make differential diagnoses necessary, often using invasive methods such as laparoscopy. Scribd is the world's largest social reading and publishing site. 11-EHC023-EF. Hysterectomy provides a definitive cure for women with symptomatic fibroids who do not wish to preserve fertility, resulting in complete resolution of symptoms and improved quality of life. Some differences among study populations may be accounted for in the model by adjusting for factors such as age distribution, demographic attributes, and the prevalence of concomitant conditions in the study sample. If your doctor is planning to use morcellation, discuss your individual risks before treatment. Patients who have underwent surgery for a hysterectomy, which is the removal of the female reproductive organs, are at risk for infection and may experience grieving . Gynecological disorders. Related financial conflicts of interest that cumulatively total greater than $1,000 will usually disqualify EPC core team investigators. Because of their role as end-users, individuals are invited to serve as Key Informants and those who present with potential conflicts may be retained. 1. Maintain frequent There is insufficient evidence on the effect of uterine artery embolization on future fertility. Larger fibroids can be removed through smaller incisions by breaking them into pieces (morcellation), which can be done inside a surgical bag, or by extending one incision to remove the fibroids. 7th ed. Nursing care plan on Uterine fibroids//Uterine fibroids/leiomyomas or myomas Nursing care plan//NCPs@Anand's nursing files @Anand's nursing files #nursingca. Table 2 includes the differential diagnosis of uterine masses.31, Treatment of uterine fibroids should be tailored to the size and location of the tumors; the patient's age, symptoms, desire to maintain fertility, and access to treatment; and the physician's experience 4,11 (Table 332 42 and Table 44,16,34,38,4044 ). Food and Drug Administration. Alternatives to hysterectomy: Management of uterine fibroids. We believe that additional evidence is needed before concluding either that the findings are stable or that the estimate of effect is close to the true effect. This is often termed the recurrence rate. View Abnormal UTERINE ACTIVITY.pptx from NURSING DIAGNOSIS at University of Nairobi. To be excluded, publication abstracts must be reviewed and excluded independently by two members of the investigative team. Warner KJ. Nursing Care Plan & Diagnosis for Hysterectomy| Risk for Infection Invited Peer Reviewers may not have any financial conflict of interest greater than $10,000. We will screen and include relevant studies with each update. Am J Obstet Gynecol. Patient-Centered Outcomes Research Institute (PCORI). A care plan is nothing more than the written documentation of the nursing process you use to solve one or more of a patient's nursing problems. 13(14)-EHC 130-EF. If you're not having severe symptoms now, you could wait until after pregnancy to have the fibroids removed. nursing care plan for uterine fibroids - MEBW information submitted for this request. Statements in the report should not be construed as endorsement by the Agency for Healthcare Research and Quality or the U.S. Department of Health and Human Services. Uterine fibroids, or leiomyomas, are the most common benign tumors in women of reproductive age.1 Their prevalence is age dependent; they can be detected in up to 80% of women by 50 years of age.2 Fibroids are the leading indication for hysterectomy, accounting for 39% of all hysterectomies performed annually in the United States.3 Although many are detected incidentally on imaging in asymptomatic women, 20% to 50% of women are symptomatic and may wish to pursue treatment.4. Uterine fibroids: Diagnosis and treatment. Expected outcomes: Pain does not exist or can be controlled . The advantage of SPRMs over GnRH agonists for preoperative adjuvant therapy is their lack of hypoestrogenic adverse effects and bone loss. Fibroids are not cancerous and are not thought to be able to become cancerous. We will upload the extracted data to the Systematic Review Data Repository (SRDR). Non-surgical management options for menorrhagia | Nursing Times Comparing Options for Management: Patient-Centered Results for Uterine Fibroids (COMPARE-UF). Hysterectomy. Unless a woman has symptoms, it's likely she does not know she has uterine fibroids. If confirmation is needed, your doctor may order an ultrasound. Fibroids can bulge from the inside or outside of the uterus ( figure 2 ). Mayo Clinic is a not-for-profit organization. We will search government and regulatory agency web sites for information on morcellation. In: Endocrinology: Adult and Pediatric. We will summarize data related to symptom status and prioritize patient-reported measures. Use of other treatments before hysterectomy for benign conditions in a statewide hospital collaborative. Small particles (embolic agents) are injected into the arteries supplying the uterus, cutting off blood flow to fibroids, causing them to shrink and die. In addition, the Key Questions address the potential harms associated with morcellation, as well as an exploration of patient and tumor characteristics that may predict success or adverse events in patients considered for morcellation. Eligible studies must report one or more patient-centered outcome (e.g., symptom improvement, blood loss, pain, quality of life). Self-reported heavy bleeding associated with uterine leiomyomata. Endometrial polyp diagnostics: tests, differential diagnosis - I Live! OK Thanks for your time and we wish you well. A single copy of these materials may be reprinted for noncommercial personal use only. Laboratory examination. Many are discovered incidentally on clinical examination or imaging in asymptomatic women. These agents significantly reduce blood loss (mean reduction = 124 mL per cycle; 95% CI, 62 to 186 mL) and improve pain relief compared with placebo,34 but are less effective in decreasing blood loss compared with the levonorgestrel-releasing intrauterine system or tranexamic acid at three months.51, Hormone Therapy. This content does not have an Arabic version. In: Current Medical Diagnosis & Treatment 2019. Uterine leiomyomas. Inpatient hysterectomy surveillance in the United States, 2000-2004. The fibroid is shaved and removed, but the uterus is left intact. In a small prospective trial of 18 patients, tamoxifen did not reduce fibroid size or uterine volume, but did reduce menstrual blood loss by 40% to 50% and decrease pelvic pain compared with the control group.56 Based on its adverse effects (e.g., hot flashes, dizziness, endometrial thickening), the authors concluded that its risks outweigh its marginal benefits for fibroid treatment. Uterine fibroids - Diagnosis and treatment - Mayo Clinic Assessing the Risk of Bias of Individual Studies in Systematic Reviews of Health Care Interventions. Nursing Care Plan-Uterine Fibroids Student: John Micahel C. Manaig Date: May 27,2021 Client: Aiken Manaig Age: 13 Sex: Male Room # 14 Assessment Nursing Diagnosis Nursing Plan Nursing Intervention Scientific Rational Expected Outcome SUBJECTIVE: Medical history, physical examination, and pelvic. During the next three to 12 months, the fibroid continues to shrink, improving symptoms. Nursing Care Plan Uterine Fibroids Many physicists using number of factors are plagued homeopathy in all other treatment must aim to eliminate. How big are they? The protocol is registered in Prospero (CRD42015025929). AHRQ Publication No. No evidence is available or the body of evidence has unacceptable deficiencies, precluding reaching a conclusion. Philadelphia, Pa.: Elsevier; 2019. https://www.clinicalkey.com. 2008 Feb;198(2):168 e1-9. Background and Objectives for the Systematic Review Topic background Most women will develop one or more uterine fibroids (i.e., leiomyomata), benign smooth muscle tumors of the uterus, during their reproductive lifespan.1 In the United States, an estimated 26 million women between the ages of 15 and 50 have uterine fibroids.1-4 More than 15 million of them will experience associated symptoms . Uterine fibroids. [Article in Japanese] Authors Y Matsumoto, S Omichi, M Arayama, N Nakamura, S Isowa. As they grow, they can distort the inside as well . Accessed April 24, 2019. Fibroids (otherwise known as myomas or leiomyomas) are abnormal non-cancerous growths in the uterus. Frequent urination (this can happen when a fibroid puts pressure on your bladder). MRI-guided focused ultrasound surgery (FUS) is: Small particles (embolic agents) are injected into the uterine artery through a small catheter. Discuss these with your doctor. Kellerman RD, et al. Hartmann KE, et al. After locating a uterine fibroid, your doctor uses another thin device to send several small needles into the fibroid. A feeling of fullness in your lower abdomen/bloating. The uterus is made of muscle, and fibroids grow from the muscle. The body of evidence has few or no deficiencies. 2015 2015-01-02 22:52:22;349:g7647. called uterine cancer, but there are other cells in the uterus that can become After 4 hours of nursing interventions, the patient will display appropriate range of feelings and lessened fear. pubmed.ncbi.nlm.nih.gov/23353618/ Mondelli B, et al. The review will focus on interventions to treat fibroids directly. When differences between the reviewers arise, we will err on the side of inclusion. 2014 May-Jun;20(3):309-33. An estimated 15% to 33% of fibroids recur after myomectomy, and approximately 10% of women undergoing myomectomy will undergo a hysterectomy within five to 10 years. PMID: 22244472, Wechter ME, Stewart EA, Myers ER, et al. In: Conn's Current Therapy 2019. In some situations, your doctor may recommend a biopsy of the uterine lining or of the mass if there's a concern for cancer. Recovery time for the patient is comparatively fast. 2014 Dec 23PMID: 25542564. A preliminary assessment of the published literature on uterine fibroid treatment suggests that limiting the search to studies published in or after 1985 does not omit critical literature. If you have symptoms, talk with your doctor about options for symptom relief. How To Manage Uterine Fibroids (Leiomyomas or Myomas) - ARC Fertility If we combine this information with your protected Robotic myomectomy gives your surgeon a magnified, 3D view of your uterus, offering more precision, flexibility and dexterity than is possible using some other techniques. Many fibroid studies have small sample sizes, which limit the ability of a study to overcome differences in baseline characteristics and variability of outcome reporting. AHRQ Publication No 01-E052 Rockville, MD: Agency for Healthcare Research and Quality. Key Informants are not involved in analyzing the evidence or writing the report and have not reviewed the report, except as given the opportunity to do so through the peer or public review mechanism. They are much smaller in size than polyps, and they also do not have a pedicel. Menorrhagia is a largely benign condition but can be emotionally and socially debilitating. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. The exact cause of uterine fibroids is still not known. There is some literature about the relationship of imaging findings and symptom profiles, but the correlation is not tight. Fibroids can grow on the inside of the uterus, within the muscle wall of the uterus, or on the outer surface of the uterus. Divergent and conflicting opinions are common and perceived as health scientific discourse that results in a thoughtful, relevant systematic review. With any procedure that doesn't remove the uterus, there's a risk that new fibroids could grow and cause symptoms. Does risk of cancer dissemination from morcellation differ by patient or fibroid characteristics (e.g., age; race/ethnicity; symptoms; menopausal status; imaging characteristics; vascular supply to fibroids; or number, size, type, location, or total volume of fibroids)? Annual costs associated with diagnosis of uterine leiomyomata. Nursing Management. Uterine atony nursing diagnosis Free Essays | Studymode If a woman does not want to have children, she can opt for endometrial ablation. We are very confident that the estimate of effect lies close to the true effect for this outcome. Uterine fibroids. Expectant management is recommended for asymptomatic patients because most fibroids decrease in size during menopause. Examples include: baseline characteristics of the patients (e.g., age, menopausal status; symptom status) and fibroid characteristics (e.g., size, volume, location, type, and vascularity). Below is the list of the 16 new NANDA Nursing Diagnoses 1. We have listed known pharmaceutical companies (Table A-1) and device manufacturers (Table A-2) in the Appendix. We will use the criteria and established tools described in the Methods Guide for Effectiveness and Comparative Effectiveness Reviews.23 Two senior investigators will assess each included study independently. Uterine fibroids can lead to gynecologic complications. If you feel like your doctor is advising a more invasive therapy, then seeing a fibroid specialist can help you ensure that you're being given all the options. Limited data have shown that they help reduce fibroid size as well as decrease menstrual bleeding, with adverse effects including hot flashes, vaginal dryness, and musculoskeletal pain.53,54 Overall, there is insufficient evidence to support the use of aromatase inhibitors for the treatment of uterine fibroids.55 Selective estrogen receptor modulators act as partial estrogen receptor agonists in bone, cardiovascular tissue, and the endometrium. Using both instruments provides your doctor with two views of a uterine fibroid, allowing for more-thorough treatment than would be possible with just one view. Removal of the ovaries eliminates the main source of the hormone estrogen . Uterine fibroids are the most common benign (not cancerous) tumors, or growths, in women of childbearing age. Any treatment that preserves the uterus means that fibroids can occur in the future. NICHD research on uterine fibroids aims to learn more about what causes them, how they grow, factors related to who develops them, and fibroid treatments. Fibroids are benign tumors that originate from the uterine smooth muscle tissue (myometrium) whose growth is dependent on estrogen and progesterone.5,6 Fibroids are rare before puberty, increase in prevalence during the reproductive years, and decrease in size after menopause.6 Aromatase in fibroid tissue allows for endogenous production of estradiol, and fibroid stem cells express estrogen and progesterone receptors that facilitate tumor growth in the presence of these hormones.5 Protective factors and risk factors for fibroid development are listed in Table 1.79 The major risk factors for fibroid development are increasing age (until menopause) and African descent.7,8 Compared with white women, black women have a higher lifetime prevalence of fibroids and more severe symptoms, which can affect their quality of life.10, Uterine fibroids are classified based on location: subserosal (projecting outside the uterus), intramural (within the myometrium), and submucosal (projecting into the uterine cavity). Management of Uterine Fibroids - Medscape Also, with magnetic resonance imaging, large uterine vessels, large nodes, are noticeable. Management of Uterine Fibroids | Effective Health Care (EHC) Program Management of Uterine Fibroids. AskMayoExpert. Changes will not be incorporated into the protocol. CARE PLAN Patient: Doris Bowman Admitted on: 3/17/2021 Medical Diagnosis: Uterine leiomyomas (fibroids) Nursing Assessment Subjective: Patient states: "I just had surgery; it hurts in my belly." Patient states: "Pain level, It's pretty bad, I'd give it a 6" Objective : Vital Signs Heart rate: 95, Blood pressure: 118/67 mm Hg. In a pelvic exam, your health care provider inserts two gloved fingers inside your vagina. We will use the same screening forms and inclusion/exclusion criteria to assess eligibility of citations recommended by peer and public reviewers and for the literature retrieved by updated literature searches. Nursing care plan on Uterine fibroids//Uterine fibroids/leiomyomas or The transcervical or through the cervix approach to radiofrequency ablation (Sonata) also uses ultrasound guidance to locate fibroids. A similar procedure called cryomyolysis freezes the fibroids. There are several surgical treatments for uterine fibroids. We will review the titles and abstracts of all publications identified through our searches against our inclusion/exclusion criteria. BMC Womens Health. Uterine Fibroids (leiomyomata) and endometriosis affect millions of women world-wide. Effect of uterine . The investigative team will also scan the reference lists of articles that are included after the full-text review phase for studies that potentially could meet our inclusion criteria. Impaired Urinary Elimination Nursing Care Plan nursing care plan guide revised 5 04 template net, nursing diagnosis for urinary tract infection uti best, 4 impaired urinary elimination chronic renal failure, . Total abdominal hysterectomy bilateral salpingo-oophorectomy (TAHBSO) is the removal of the entire uterus, the ovaries, fallopian tubes, and the cervix. MARIA SYL D. DE LA CRUZ, MD, AND EDWARD M. BUCHANAN, MD. Newer approaches to random effects meta-analysis, such as latent Dirichlet process and Gaussian process models, allow for robust (e.g., non-parametric) estimates of variation that do not rely on the assumption of normally distributed random effects. An ultrasound probe gets images of the inside of the uterus to check for anything unusual. Accessed April 24, 2019. HHSA 290-2015-00003I from the Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services. So far, there's no scientific evidence to support the effectiveness of these techniques. Abnormal UTERINE ACTIVITY.pptx - KENNEDY K. ABNORMAL Nursing Diagnosis Infertility If you ally dependence such a referred Nursing Diagnosis Infertility book that will pay for you worth, get the completely best seller from us currently from several preferred authors. The uterus is anatomically divided into 3 regions; the fundus (uppermost part), the body (main part), and the cervix (lower part). Copyright 2023 American Academy of Family Physicians. Nursing Care Plan for Reproductive System Disorders : Uterine Fibroids Lyceum-Northwestern . In: Williams Gynecology. 2008 Jan;198(1):34 e1-7. Adenomyosis: Diagnosis and Management | AAFP Obstet Gynecol. Am J Obstet Gynecol. Comments did not necessitate any significant changes to the Key Questions, review scope, or inclusion criteria. The draft Key Questions were posted for public comments (6/23/15 7/13/15). 2006 Oct;108(4):930-7. The authors of this report are responsible for its content. Risk for Allergy Response 4. Potential Peer Reviewers must disclose any financial conflicts of interest greater than $10,000 and any other relevant business or professional conflicts of interest. Expectant management is appropriate for women with asymptomatic uterine fibroids. Uterine fibroids are benign uterine tumors of smooth muscle origin. Rockville, MD 20857 In the postpartum period, women with fibroids have an increased risk of postpartum hemorrhage secondary to an increased risk of uterine atony.20 The risk of malignancy for uterine fibroids is very low; the prevalence of leiomyosarcoma is estimated at about one in 400 (0.25%) women undergoing surgery for fibroids.21 Because the natural course of fibroids involves growth and regression, enlarging fibroids are not an indication for removal.22,23, The evaluation of fibroids is based mainly on the patient's presenting symptoms: abnormal menstrual bleeding, bulk symptoms, pelvic pain, or findings suggestive of anemia. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). If fibroid treatment is needed and you want to preserve your fertility myomectomy is generally the treatment of choice. Start Here. We will search web sites of organizations likely to conduct research, issue guidance, or generate policies relevant to management of uterine fibroids (Table A-5 in the Appendix). Journal of Obstetrics and Gynaecology Canada. Uterine leiomyomata, or fibroids, are benign tumors of the uterus made up of smooth muscle and the extracellular matrix proteins collagen and elastin. Help with Care Plans - General Students, Support - allnurses The Care Plan of Uterine Fibroids - Nursing Student Assistance - allnurses Zimmermann A, Bernuit D, Gerlinger C, et al. Although studies have had conflicting results on the change in fibroid size during pregnancy,17,18 a large retrospective study of women with uterine fibroids found a significantly increased risk of cesarean delivery compared with a control group (33.1% vs. 24.2%), as well as increases in the risk of breech presentation (5.3% vs. 3.1%), pre-term premature rupture of membranes (3.3% vs. 2.4%), delivery before 37 weeks' gestation (15.1% vs. 10.5%), and intrauterine fetal death with growth restriction (3.9% vs. 1.5%).19 Therefore, fibroids in pregnant women warrant additional maternal and fetal surveillance. Uterine leiomyomata (fibroids, myoma). We will assess the applicability of findings reported in the included literature to the general population of women with uterine fibroids by determining the population, intervention, comparator, and setting in each study and developing an overview of these elements for each intervention category. Medical therapy to reduce heavy menstrual bleeding includes hormonal contraceptives, tranexamic acid, and nonsteroidal anti-inflammatory drugs. For studies that meet the eligibility criteria from the full-text review assessment, we will extract study characteristics (e.g., study design, year, setting, funding source, etc. Methods Guide for Effectiveness and Comparative Effectiveness Reviews. Hi, I'm Dr. Michelle Louie, a minimally invasive gynecologic surgeon at Mayo Clinic. Also, uterine artery embolization and radiofrequency ablation may not be the best options if you're trying to optimize future fertility.
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